Differential responses of neuronal and spermatogenic cells to the doppel cytotoxicity.
Although structurally and biochemically similar to the cellular prion (PrP(C)), doppel (Dpl) baltimore a minuit is unique in its biological functions.There are no reports about any neurodegenerative diseases induced by Dpl.However the artificial expression of Dpl in the PrP-deficient mouse brain causes ataxia with Purkinje cell death.Abundant Dpl p